Flashcard Set Preview
| Side A | Side B | ||
| 1 |
big plaque
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atheroma
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| 2 |
smooth muscle cells
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media
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| 3 |
adventitia
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outer core
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| 4 |
lots of cholesterol
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fatty streak
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| 5 |
- thrombosis
- blood
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atherogenesis
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| 6 |
the formation of atheromas on the walls of the arteries
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atheromas
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| 7 |
________ not merely filled with lipids, but contain cells whose functions critically influence...
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atheroma
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| 8 |
intrinsic vascular wall cells (2)
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1. endothelium
2. smooth muscle cells
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| 9 |
inflammatory cells (3)
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1. macrophages
2. T lymphocytes
3. mast cells
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| 10 |
tendency of a material to coe in contact with the blood and produce a:
- thrombus (clot)
-...
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throbogenicity
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| 11 |
Virchow's triad (3)
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1. hemodynamic changes (stasis, turbulence)
2. endothelial injury/dysfunction
3. hypercoagulability...
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| 12 |
erythrocytes, O2 carriers
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RBC
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| 13 |
WBC (3)
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1. neutrophils
2. eosinophils
3. lymphocytes
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| 14 |
platelets (1)
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thrombocytes
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| 15 |
plasma
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carrier
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| 16 |
tunica intima (2)
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1. endothelium
2. SM
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| 17 |
tunica media (2)
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1. SM
2. collagen
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| 18 |
tunica adventitia (1)
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1. loose connective tissue
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| 19 |
3 endothelial layers
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1. tunica intima
2. tunica media
3. tunica adventitia
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| 20 |
a single-cell lining covering the internal surface of blood vessels, cardiac valves, and numerous...
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endothelium
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| 21 |
location allows it to sense changes in hemodymanic forces and blood-borne signals and respond...
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endothelium
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| 22 |
inflammatory response (3)
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1. dilation of capillaries to increase blood flow
2. micro vascular structural changes and...
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| 23 |
immune response (4)
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1. much more specific than inflammatory response
2. involves memory and specificity
3. antigen/antibody...
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| 24 |
Endothelium functions (4)
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1. vessel integrity
2. regulates permeability
3. vasocontriction
4. vasodilation
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| 25 |
Endothelium produces (4)
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1. vasoconstrictors
2. vasodilators
3. pro-thrombotic, anti-thrombotic and fibrinolytic substances
4....
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| 26 |
endothelin (Et-1)
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vasocontrictor
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| 27 |
- NO
- prostacyclin (PGI2)
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vasodilators
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| 28 |
adhesion molecules (3)
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1. platelets
2. monocytes
3. lymphocytes
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| 29 |
injury to endothelium, causes generalized damage (4)
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1. TC and TG
2. hypertension
3. smoking
4. excess LDL
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| 30 |
all atherogenesis is related to an inflammatory response to ________
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endothelial damage
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