Inflammation And Tissue Repair

Chapter 2 Phy Sical Ag

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Side ASide B
What is the 3 main phases of healing?
1. Inflammation phase 2. Proliferation phase 3. Maturation phase
What is inflammmation phase? last?
It's the first phase of healing. prepares the wound for healing Lasts 1-6 days from injury
What is proliferation phase? last?
second phase of healing. rebuilds the damaged structures and strengthenes the wound Lasts...
What is the maturation phase? how long does it last? timeline applies?
3rd phase of healing modifies the scar tissues into its mature form, 9 on (1-2 years) This...
Major events in inflammation phse?
1.vasoconstriction 2. vasodilation 3. clot formation 4. phagocytosis
Major events in proliferation phase?
1.epitheliaziation 2. fibroplasias/ collagen production 3. wound contracture 4. neovascularization
Major events in maturation phase?
1. Synthesis/ lysis balance, 2. Collagen fiber orientation, 3. Healed injury
What is the Primary purpose of inflammation?
It's an immediate protective response attempt to destroy dilute or isolate the cells or agents...
cardinal signs of inflammation (English and Latin) and give the cause of each.
heat                    Calor             Increase...
english : loss of function
Latin : factio laesa pian and swelling
explain the affects of  vasoactive mediators
increase  vascular permeablity, edema
chemotactic factors
recruitment/ stimulation of inflammatory cells, acute inflammation PMSs, platelets; chronic...
platelets and the coagulation system?
thrombus formation, vasoactive mediators (vascular permeability)
what is Role of neutrophils?
predominate and release a number of factors that amplify  the platelet aggregation response,...
replace neutrophils after 2 days from injury
are WBC that histamine attracts to the damaged tissue area
monocytes turn into macrphages
Identify the most important cell in the inflammatory phase?
Summerize  the major events in the inflmmatory phase?
vascular: vasodilation followed by vasocontriction at the capillaries, post capillary venules,...
retraction and sealing off of blood vessels, platelets form clots and assist in building of...
delivery of leukocytes to the area of injur to rid the area of bacteria and debris by phagocytosis....
mediated by both cellular and humoral factors. activiation of the complrement system viathe...

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