Immunohematology

Flashcards for Immunology studying

194 cards   |   Total Attempts: 182
  

Cards In This Set

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Antibodies are produced by
B cells
The chemical composition of an antibody is
Protein
In a hemagglutination test, the antigen is located where?
On the RBC membrane
Agglutination rxns characterized by many small agglutinates in a background of free cells would be graded in a tube setting as: 1+, 2+, 3+, 4+
1+
Why are patient RBCs washed before the addition of AHG reagents in the DAT?
To remove unbound serum proteins
The IAT requires incubation at 37 C. What is the purpose of this incubation step?
Allow time for IgG antibodies to attach to antigens on the RBCs
Questions 7-11 match the corect immunoglobulin class
Class: a) IgA b) IgD c) IgE d) IgG e) IgM
Produced early in an immune response
E) IgM
Found predominantly in secretions
A) IgA
Cross the placenta
D) IgG
Pentameric in shape
E) IgM
Fixes complement most efficiently
E) IgM
What is the most common reason for a positive Rh control tube when using a high protein anti-D reagent?
Positive DAT
Monospecific AHG reagents contain what?
Either anti-IgG or anti-C3 antibody
You've added CC after performing an IAT on a pt. You observe agglutination in the tube. What situation was NOT controlled for in testing by adding these CC?
Addition of patient serum