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Related Topics
Cards In This Set
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Who should get corticosteroids?/
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Joint disorders. inflammatory disorders. inflammatory bowel disease, misc inflammatory disorders:bursitis, tendonitis, ophthalmic disorders. allergic reactions, and respiratory disorders, as well as dermatologic disorders. nuerou disorders, adrenal insufficiency, premies, neoplastic disease to suprress lymphocytes
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Why would you give a newborn baby a corticosteroids?
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Prevention of Respiratory Distress Syndrome in Preterm Infants. BECAUSE ADRENAL GLANDS ARE NOT FUNCTIONAL ENOUGH TO RELEASE CORTICOSTEROIDS. MOM CAN BE GIVEN SHOT OF STEROIDS TO AID IN THIS.
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By giving corticosteroids, what happens to the adrenal glands?
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they stop functioning. negative feedback. they shut down production, therefore they can go into withdrawl if abruptly stopped.
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What drugs cause osteoporosis? why?
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Suppression of osteoblasts
Accelerate osteoclasts
Reduce intestinal absorption of Ca
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Drug of choice for PCP
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Bactrim. sulfonamide
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What does corticosteroids affect the metabolism of?
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Carbohydrrates
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Increase risk for what if taking corticosteroids? what intolerance may develope?
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PCP - Pneumocystis carinii pneumonia (PCP) is growing in patients receiving steroids
Glucose intolerance and DM may develop
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Due to high breakdown of protein, what may occur with corticosteroids?
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Muscle weakness, especially the arms and legs (can be severe enough to prevent ambulation).
May need extra protein supplementation. |
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Awhat disturbances may occur with corticosteroids?
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Na and Water retention
K loss
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Other side effects. of glucocorticoids.
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Behavior and personality may change personality and mood (esp. with long-term therapy). Euphoria, hallucinations, depression, mania, etc.).
Cataracts and Glaucoma
Peptic Ulcer Disease
Long-term therapy can cause a Cushingoid syndrome because of the changes in muscle and fat deposition and use. It's similar to Cushing's disease (hypercortisolism). The effects include a change in the shape of the body (round face, enlarged abdomen,
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Long-term therapy of glucocorticoids can cause
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A Cushingoid syndrome because of the changes in muscle and fat deposition and use. It's similar to Cushing's disease (hypercortisolism). The effects include a change in the shape of the body (round face, enlarged abdomen,
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Do you see the same se with topical or inhaled steroids?
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No! hence why we can give to children.
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Who not to give steroids too
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Systemic fungal infections. (because of immunocompromise)
Cautious use in patients:
At risk for infections (may decrease resistance), and those with infections (may mask s&s, and impair healing)
With diabetes mellitus (hyperglycemia)
Peptic ulcer dz
Hypertension
Children
Osteoporosis
CHF
Liver disease- increases the biologic and toxic effects of the drugs
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Drug interactions
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Watch for drugs that affect fluid and electrolyte balance like diuretics. If on anti-arrhythmic drugs like digoxin, watch potassium levels very carefully.
NSAIDS can increase the risk of gastric ulcers.
Insulin or oral hypoglycemic dosages may need to be increased.
Vaccines-body cannot necessarily handle. may not be abl to do anything with a low dose.
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Prototype of glucocorticoids
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Hydrocortisone- Prototype
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