General Biology Chapter 14

General Biology
Created Oct 31, 2011
by dspencer
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Advantages of pea plants for genetic study
Many VarietiesMating can be controlledEach flower has sperm-producing(stamen) organs and egg...
plants that produce offspring of the samevariety when they self-pollinate
True-breeding
Mendel mated twocontrasting, true-breeding varieties, a processcalled________
Hybridization
The true-breeding parents are the_________
P generation
The hybrid offspring of the P generation are calledthe_____________
F1 generation
When F1 individuals self-pollinate or crosspollinatewith other F1 hybrids, the ____________is...
F2 generation
alternative versions of genes
alleles
Each gene resides at a specific ______ on aspecific chromosome
locus
the two alleles for a heritable character separate(segregate) during gamete formation and end...
Law of segregation
a diagram for predicting the results of a genetic cross between individuals of known...
Punnett Spuare
An organism with two identical alleles for acharacter is said to be________ for the gene controlling...
homozygous
An organism that has two different alleles for agene is said to be __________ for the genecontrolling...
heterozygous
____________ are not true-breeding
Heterozygotes 
physical appearance
Phenotype
Genetic Makeup
GenotypeIn the example of flower color in pea plants, PPand Pp plants have the same phenotype...
How can we tell the genotype of an individual withthe dominant phenotype?
TestcrossThe answer is to carry out a testcross: breedingthe mystery individual with a homozygousrecessive...
individuals that are heterozygous for one character
Monohybrids
Crossing two true-breeding parents differing in twocharacters produces __________
Dihybrids
a cross between F1 dihybrids
Dihybrid cross
states that each pair of alleles segregates independently of each other pair of alleles...
Law of independent assortment
Mendel’s laws of segregation and independentassortment reflect the rules of _______
probability 
The _____________ states that the probabilitythat two or more independent events will occurtogether...
multiplication rule
Probability in an F1 monohybrid cross can bedetermined using__________
the multiplication rule 
The ___________ states that the probability thatany one of two or more exclusive events willoccur...
addition rule
The___________ can be used to figure out theprobability that an F2 plant from a monohybridcross...
 rule of addition
A dihybrid or other multicharacter cross isequivalent to two or more independent____________...
monohybrid crosses 
In calculating the chances for various genotypes,each character is considered separately, andthen...
multiplied
Inheritance of characters by a single gene maydeviate from simple Mendelian patterns in the...
– When alleles are not completely dominant orrecessive– When a gene has more than two alleles–...
___________occurs when phenotypesof the heterozygote and dominant homozygote areidentical
Complete dominance
___________the phenotype of F1hybrids is somewhere between the phenotypes ofthe two parental...
incomplete dominance
In _____________, two dominant alleles affect thephenotype in separate, distinguishable ways
codominance
________ are simply variations in a gene’snucleotide sequence
Alleles 
For any character, dominance/recessivenessrelationships of alleles depend on the level atwhich...
phenotype
a dysfunctional enzyme causes an accumulation of lipids in the brain
Tay-Sachs disease
Most ______exist in populations in more than twoallelic forms
genes
Most genes have multiple phenotypic effects, aproperty called______
PleiotropyFor example, pleiotropic alleles are responsible forthe multiple symptoms of certain...
in ______________a gene at one locus alters thephenotypic expression of a gene at a secondlocus
Epistasis 
_______________are those that vary in thepopulation along a continuum
quantitative characters
Quantitative variation usually indicates ___________, an additive effect of two or moregenes...
polygenic inheritanceSkin color in humans is an example of polygenicinheritance
The ______________ is the phenotypic rangeof a genotype influenced by the environment
norm of reactionFor example, hydrangea flowers of the samegenotype range from blue-violet to...
Norms of reaction are generally broadest forpolygenic characters, such characters are called...
multifactorial
An organism’s phenotype includes:
Physical appearanceInternal anatomyPhysiologybehavior
Why aren't humans good subjects for geneticresearch?
– Generation time is too long– Parents produce relatively few offspring– Breeding experiments...
Inheritance patterns of particular traits can betraced and described using _______________
Pedigrees 
Many genetic disorders are inherited in a __________ manner
Recessive 
___________are heterozygous individuals whocarry the recessive allele but are phenotypicallynormal
Carriers 
Recessively inherited disorders show up only inindividuals ____________ for the allele
homozygous
_______________ (i.e., matingsbetween close relatives) increase the chanceof mating between...
Consanguineous mating
____________ is the most common lethalgenetic disease in the United States
Cystic Fibrosis 
The disease is caused by the substitution of asingle amino acid in the hemoglobin protein inred...
Sickle-cell disease 
Dominant alleles that cause a lethal diseaseare rare and arise by __________
mutation
In _________________, a sampleof the placenta is removed and tested
chorionic villus sampling (CVS)
In _____________, the liquid that bathes thefetus is removed and tested
amniocentesis


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