Flashcard Set Preview
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| 1 |
Q: What 4 Things
is the Fungal Cell Wall made of?
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A: Chitin (NAG), Mannan, and Glucan (polymer of D
glucose), Hydrophobins (for adherence)...
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| 2 |
Q: What is a
unique component of fungal cell membranes?
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A: Ergosterol
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| 3 |
Q: What does
Caspofungin attack as an antifungal drug?
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A: Glucan
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Q: Dimorphic fungi
can exist in two forms: As unicellular Yeast and as multicellular...
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A: Yeast form.
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Q: Mycelia (molds)
are made up of Hyphae. Hyphae can be septate or aseptate. What...
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A: Coenocytic
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| 6 |
Q: What are four
ways you can classify fungi based on mode of reproduction?
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A: ascomycota (sexual), Basidiomycota (sexual),
Zygomycota (both sexual and asexual),...
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Q: Hyphae can reproduce by asexual or sexual
reproductive structures. What are they called?
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A: Asexual reproductive structures are called conidia.
Sexual reproductive structures...
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| 8 |
Q: What fungal
components act as PAMPS, stimulating a nonspecific innate response?
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A: cell wall (i.e. chitin, mannan, glucan), spores
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| 9 |
Q: What fungal
component induces an adaptive response that is not effective?
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A: Hydrophobins
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| 10 |
Q: What fungal
components induces an adaptive response that is effective?
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A: Capsules, Exoenzymes, and Exotoxins.
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| 11 |
Q: The Th1 response to fungal infections lead to
the production of what cytokine?
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A: gamma interferon, which activates macrophages
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| 12 |
Q: The immune
response to fungi can be very different depending on the type of response,
Th1/inflammation,...
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A: Th1/strong inflammatory response leads to resolution
of infection.
Th2/weak...
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| 13 |
Q: What are the
symptoms of Sporothrix Schenkii infection?
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A: skin lesions that may lead to necrosis or ulcers.
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| 14 |
Q: What are the
symptoms of Coccidiodes immitis infection?
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A: fever, cough, and may lead to pneumonia in
immunocompromised patients. It can lead...
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| 15 |
Q: Which part of the Coccidiodes immitis causes
the disease?
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A: The spherule. You inhale the spores to get the
disease.
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