Fluid/Electrolyte/acid Base Balance


Fluid Electrolyte Balance
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hydrophilic
 
A molecule that is polar and attracts water and easily dissolves in water.
hydrophobic
 
molecule that don't dissolve in water because they are nonpolar (lipids)
Phospholipid
 
part of plasma membrane with hydrophilic heads and hydrophobic tails facing inward, sandwich style. Impermeale to hydrophilic molecules, ions used for salt and pH balance must be pumped in using ion protein pumps.
ICF2
 
2/3 of our fulids in ICF. chemical reactions for metabolism happen here, overall negative charge. Major molecules: Mg+, **K+**, PO3^4-
ECF
 
all body fluid outside of the cells. 1/3 of our fluid. Major molecules: **NA+**, NACO3-, Cl-
interstital fluid
 
Fluid outside of the 80% of our ECF is interstitial.
Hydrostatic pressure
 
forces fluid out of a space due to pressure.
osmotic pressure
 
fluid flows into a space via osmosis (presence of solutes)
osmosis
 
movement of water from an area of lower solute concentration to an area of higher concentration
Osmolarity
 
unit of concentration, measured in Osmoles per Liter (think moles from chemistry)
water balance
 
daily water intake must equal output. water gain vs. water loss.
water gain
 
in hypothalmus monitor ECF osmolarity and when it gets too high, it stimulates the cortex to create thirsty sensation. Which also stimulates hypothalmus to release ADH. ADH stimulates kidney aquaporin production to release water and lower osmolarity

The kidneys function to absorb more water if dehydrated (make urine more concentrated), which will eventually trigger osmoreceptors to start loop again... NEGATIVE FEEDBACK
water loss
 
negative feedback loop between hypothalmus and kidneys. kidneys reabsorb water if too much water and dilute/excrete in urine, and absorb if dehydrated, making uring more concentrated to conserve water.
sensible/insensible water loss
 
sensible - noticeable, sweat, urine, feces, etc.
insensible - light perspiration, and respiration.
adh
 
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