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Etomidate - Pharmacology

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Created By
abbyas2003
103 days ago
Etomidate - Pharmacology
 
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1. Cardiovascular Effects1. no ____ / effects2.... 1. CV/ hemodyn2. ischemic, valve D/o's, CHF3....   11. 1. Large Dose; 0.6mg/kg provides ___ level... 1. deep/ anesthesia/ intubation2a. cardioversionb....
2. 1. carrier of etomidate and its possible... 1. propylene glycol = small degree of hemolysis,...   12. Other Effects1. 4 major adverse effects when... 1. PONV, pain on injection, myoclonic mvmt,...
3. 1. best way to reduce occurrence of myoclonus/... 1. pre-medication (opioid or BZD)2. NDNB3....   13. 1. 2 studies r/t etomidate and adrenocort... 1. cortisol lvls slightly lower than pre-induction...
4. 1. high incidence of ____ mvmt2. effect on... 1. myoclonic2. similar to Inh agents. dose...   14. Resp Effects1. ___ effect on ventilation2.... 1. minimal2. histamine3. VRCO24. often= brief...
5. Endocrine1. what can result from long term... 1. adrenocortical suppression2. dose-dependent,...   15. 1. primary action on CNS is ____2. no ___... 1. hypnosis2. analgesic3. B2 & B3 more...
6. 1. dcrs'd ICP is maintained period following... 1. intubation2. high dose infusion (60mcg/kg/min)3....   16. Metabolism1. 2 ways2. main metabolite3. excretion 1. in liver by ester hydrolysis to carboxylic...
7. 1. induction dose2. onset3. relationship... 1. 0.2- 0.6mg/kg2. rapid3. directly related 4....   17. 1. administration for children?2. advantage? 1. induction by rectal administration (6.5mg/kg)2....
8. Pharmacokinetics- 3 compartment model1. distribution... 1. 2.7 min2. 29 min3. 2.9- 5.3hrs4. 10min   18. Clearance1. ____= high; ____ ml/kg/min2.... 1. hepatic/ 18-25 (greater than liver bld...
9. Advantages1. ____ stability2. minimal ___... 1. hemodynamic2. resp depression3. cerebral4....   19. Disadvantages1. temporary inhibition of what?2.... 1. steroid synthesis (after single dose and...
10. Physiochemical Characteristics1. ___ and... 1. water insoluble and unstable2. solvent3....   20. Infusion:1. stable ____ ____2. adequate ___... 1. hemodynamic status2. spont respirations3....
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