Chemistry - Endocrinology

Endocrinology Notes for Final Exam - Dec 8 2008

72 cards   |   Total Attempts: 183
  

Cards In This Set

Front Back
What are the 3 classes of hormones?
Peptides, steroids, amines
What class of hormones does insulin or beta-HCG belong to?
Peptides
How/when are peptide hormones made?
Made by using enzymes to cleave precursor units. Made in advance & stored in granules until needed.
What class of hormones does testosterone, estrogen, aldosterone, cortisol, FSH belong to?
Steroids
What are steroid hormones composed of/made from?
Lipids (cholesterol)
Are steroid hormones stored in cells until needed?
No storage, just made when required.
What class of hormones does epinephrine belong to?
Amines
What are amine hormones made from?
Tyrosine
Where are peptide hormones made?
Pituitary, pancreas, parathyroid, heart, stomach, liver, kidney
Where are steroid hormones made?
Adrenal cortex, gonads, placenta
Where are amine hormones made?
Adrenal medulla, thyroid
How do non-steroid hormones trigger a response in a cell?
Bind to PM receptor, trigger cascade (secondary msngers - CAMP, etc)
How do steroid hormones trigger a response in a cell?
Cross PM, bind to nuclear receptors, activate specific genes for transcription.
What is the difference btw a heterogenous & homogenous immunoassay?
Heterogenous requires washing
What does nephelometry measure? turbidometry?
Light scatter; decreased light transmission (or increased absorbance)