Bortadella, Brucella, Nocardia

15 cards

The deets on these 3 critters


 
  
Created Oct 14, 2010
by
scocciardi

 

 
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1
What is the pathogenesis of Whooping Cough like (its toxins and their paths)?
 
Pertussis Toxin is the main virulent factor - it helps Bordetella attach to cilia cells in...
2
This phase of Whooping Cough is characterized by profuse runny nose.
 
Catarrhal Phase (first phase) - 1-2 weeks, when its most contagious; only period of antibiotic...
3
What is the key characteristics (2) of the Paroxysmal Phase of Whooping Cough, and how long...
 
The "whoop" cough, and post-tosis vomitting.  Last 2-10 weeks.   
4
What is different about the new DPaT Vaccine (instead of just the DPT vaccine)?
 
DPaT has an acellular Pertusis component - it uses the purified protein pertussis...
5
How is Whooping Cough detected in lab today?  What used to be popular (what name of Agar...
 
PCR detection of bacterial DNA.  Before - Nasopharyngeal Swab, grow it on a Bordet-Gengou...
6
Who is most at risk for getting Bordetella pertussis?  
 
Infants <1 year-old.  No immunity built-up.  The immune adult can still pass it...
7
Give 2 types of people who would most likely present with Brucellosis.
 
1) The butcher (contracted it from cattle or cattle aborted placenta maybe).  2)Traveler...
8
What is Brucellosis?  Does this fever peak in the evening or in the morning?
 
Brucellosis = Undulating Fever.  Peaks at night, goes away in morning.  
9
What is the relationship between Reticuloendothelial Cells and Brucella?  
 
Brucella is an intracellular organism - lives within the macrophages of Reticuloendothelial...
10
What are 2 ways of preventing Brucella abortus?
 
Pastuerize milk.  Give all cattle a live attenuated B. abortus vaccine (this is done in...
11
What antibiotic(s) would you treat Brucellosis infection?
 
Combination of Tetracycline (Doxycycline) + Aminoglycoside or Rifampin.  *Note: Beta-lactams...
12
What is the difference in transmission between Nocardia brasiliensis and Nocardia actinomyces?
 
N. brasiliensis is contracted cutaneously through direct inoculation.  N. actinomyces...
13
What is one risk factor (characteristic) that someone may have to increase their chance of...
 
1) Chronic respiratory problems - increases risk of resp. contraction of N. actionomyces and...
14
Besides Pneumonia, what is another main clinical presentation with Nocardia actinomyces?
 
Abcesses on the brain, kidney or lung. 
15
Morphologically, why is Nocardia often confused with Tuberculosis?
 
They are both Acid-Fast.

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