Flashcard Set Preview
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| 1 |
What are the four components of cellular membranes?
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phospholipid bilayer, transmembrane proteins, Interior protein network, cell surface...
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why is the phospholipid important in cellular membrane?
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because it's made with cholesterol
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why are the transmembrane proteins important in the cellular membrane?
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pass through lipid bilayer
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Why is the interior protein network important in the cellular membrane?
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gives cell shape, anchors proteins
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why are cell surface markers important in the cellular membrane?
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used for cell-cell recognition
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| 6 |
basic structure of phospholipids
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polar hydrophilic head and two fatty acid tails
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| 7 |
Membrane Fluidity
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ability of proteins and PLs to move laterally in membrane
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What factors affect membrane fluidity?
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length of FA tails (shorter then moves faster), unsaturated FA tails increases fluidity, increase...
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| 9 |
Fluid mosaic model
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model for how proteins and phospholipids are arranged in membrane. singer & nicholson proud...
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name the membrane proteins
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peripheral membrane proteins, integral membrane proteins
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| 11 |
peripheral membrane proteins
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associate with membranes but don't pass through
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| 12 |
transmembrane proteins
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span the lipid bilayer, hydrophobic (alpha helixes and beta sheet)
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| 13 |
How do molecules get through the PM?
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transport, enzymatic activity, signal transduction, cell-cell recognition, intercellular joining,...
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Passive transport
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requires no ATP, molecules follow concentration gradient
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Passive diffusion
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gases and small uncharged molecules
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Facilitated diffusion
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passage of molecules across a membrane with help from transporter proteins, requires no energy.
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| 17 |
carrier proteins in Passive Transport
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bind to specific molecules and change shape and spit molecules out on other side
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| 18 |
channel proteins in passive transport
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allow certain molecule through the pore
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Types of Channel proteins
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non-gated ion channels, gated ion channels
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non-gated ion channels
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always open or flicker between open and close
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gated ion channels
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open or close in response to a stimulus chemically or electrically
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| 22 |
Osmosis
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diffusion of water across membrane
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| 23 |
hypertonic vs hypotonic vs isotonic
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hyper - higher concentrationhypotonic - low concentrationioso - equal concentration
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