Benzodiazepines: Properties

14 cards

Properties of benzodiazepines required for knowledge of pharmacology for primary FRCA


 
  
Created Dec 7, 2010
by
007wendy

 

 
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1
half life diazepam
 
24-48h
2
half life clonazepam
 
24-48h
3
half life midazolam 
 
1-3h
4
half life oxazepam 
 
3-8h
5
half life temazepam
 
6-8h
6
half life lorazepam 
 
12h
7
VD diazepam
 
1litre/kg
8
diazepam clearance
 
0.4ml/min/kg
9
diazepam % protein bound
 
99%
10
midazolam % protein bound
 
96%
11
midazolam VD
 
1litre/kg
12
Clearance midazolam
 
7ml/min/kg
13
midazolam bioavailibility, oral, IM
 
oral: 44%, IM 80-100%
14
receptor site where benzo's work:
 
GABA A receptor: alpha/gamma interface

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