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Side A
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Side B
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Side A
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Side B
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| 1. |
acyclovir is what kind of drug? |
antiherpes |
|
10. |
mechanism of acyclovir |
phosphorylation to the triphosphate form;... |
2. |
acyclovir uses? |
genital herpes, varicella, herpes zoster, |
|
11. |
acyclovir adverse effects |
headache nausea, diarrhea - oraldelirium,... |
3. |
zidovidine |
NRTI - nucleotide reverse transcriptase inhibitor |
|
12. |
Zidovidine mechanism of action |
undergoes three phosphorylations by host... |
4. |
zidovidine clinical uses |
AIDS; HIV; prophylaxis of exposed healthcare... |
|
13. |
zidovidine adverse effects |
bone marrow suppresion, GI intolerance, headache... |
5. |
tenofovir
|
Nucleotide RTI, fewer phosphorylations required... |
|
14. |
efavirenz, nevirapine, delaviridine |
non nucleoside RTI, inhibit reverse transcriptase... |
6. |
0Nucleoside RTIs (same as zidovidine |
stavudine, didanosine, lamivudine,zalcalcitabine,abacavir |
|
15. |
adverse effects common to NRTIs |
hepatomegaly, lactic acidosis, fatty liver,... |
7. |
ritonavir |
protease inhibitor |
|
16. |
ritonavir mechanism of action |
inhibits HIV protease which is necessary... |
8. |
adverse effects of ritonavir |
GI intolerance, paresthia, elevated serum... |
|
17. |
ritonavir drug interactions - accelerate... |
rifampin and rifabutin |
9. |
ritonavir inhibits actions of and increases... |
lovastatin, simvastatin, clarithromycin,... |
|
18. |
adverse effects common to PI |
lipodystrophy, insulin resistance and hyperglycemia |
