Anatomy Unit 3 Part 2

105 cards

chap 11 muscl es unit


 
  
Created Jul 8, 2010
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cmdennis

 

 
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1
Universal Characteristics of Muscle (5)
 
- responsiveness - conductivity - contractability - extensibility - elasticity
2
Responsiveness
 
- (excitability) - capable of response to chemical signals, stretch or other signals, and...
3
Conductivity
 
local electrical charge triggers a wave of excitation that travels along the muscle fiber
4
Contractility
 
shortens when stimulated
5
Extensibility
 
capable of being stretched
6
elasticity
 
returns to its original resting length after being stretched  
7
Myofibers (muscle fibers)
 
- voluntary striated muscle attached to bones - as long as 30 cm
8
Muscle fiber drawing
 
page 406
9
Triad
 
T tubule and 2 terminal cisternae
10
Active Site
 
region of a protein that binds to a ligand
11
Sarcolemma
 
plasme membrane tunnel like T-tibules that penetrate the cell carry electric current to cell...
12
Sarcoplasm
 
cytoplasm contains myofibrils, glycogen, myoglobin, mitochondria
13
Sarcoplasmic Reticulum
 
smooth endoplasmic reticulum network around each myofibril
14
Myofibrils
 
bundles of parallel protein microfilaments called myofilaments
15
Myofilaments
 
3 types: thick, thin, elastic
16
Terminal Cisternae
 
dilated end sacs that store calcium
17
Thick filaments
 
made up of ab. 500 myosin molecules 2 intertwined polypeptides (golf clubs) arranged in a...
18
Bare Zone
 
central area with no heads
19
Thin Filaments
 
2 intertwined strands of fibrous actin (string of golf balls) have active site for tropomyosin...
20
G Actin (globular)
 
a subunit of fibrous actin with an active site (individual golf ball)
21
Tropomyosin
 
a "bar" that blocks the active sites for G actin
22
Troponin
 
"pad-lock" calcium binding molecule stuck to each tropomyosin molecule
23
Elastic Filaments
 
keeps thick and thin filaments aligned with each other resists overstretching helps the cell...
24
Titin
 
huge springy protein runs through core of each thick filament connects thick filament to...
25
Contractile Protein
 
does the work ex: myosin and actin
26
Regulatory Protein
 
ex: troponin and tropomyosin act like a switch that starts and stops shortening of muscle...
27
Accessory Protein
 
ex: dystrophin links actin of outermost myofilament to peripheral protein
28
Striations
 
myosin and actin organized in a precise way to produce dark and light bands due to overlapping
29
A Band
 
dark band of striation think and thin filaments overlap
30
I Band
 
light band of striation thin and elastic filaments overlap
31
Sarcomere
 
the segment of the  myofibril from one Z disc to another
32
Motor Unit
 
motor neuron and the muscle fibers it innervates
33
Small Motor Unit
 
fine degree of control ex: writing tiny letters
34
Large Motor Unit
 
more strength than control powerful contractions supplied by large motor units ex: kicking...
35
Synapse
 
point where a nerve fiber meets its target cell
36
Neuromuscular Junction
 
when target cell is a muscle fiber
37
Neuromuscular Junction Drawing
 
p. 411
38
Synaptic knob
 
swollen end of a nerve fiber contains synaptic vessicles with acetylcholine ACh released...
39
synaptic cleft
 
tiny gap between synaptic knob and muscle sarcolemma
40
Schwann Cell
 
envelops and isolates all of the NMJ from surrounding tissue fluid prevents leakage
41
Basal Lamina
 
thin layer of collagen and glycoprotein separates schwann cell and entire muscle from surrounding...
42
Polarized
 
having a charge
43
Resting Membrane Potential
 
due to Na outside of cell and K and other anions inside of cell -90 mV maintained by the sodium...
44
Depolarization
 
moving away from -90 mV ion gates open allowing Na to rush into cell makind ICF briefly positive
45
Repolarization
 
going back towards -90 mV K rushes out of cell making ICF negaitve again
46
Action Potential
 
quick up and down voltage shift
47
4 Actions involved in muscle contraction and relaxation
 
1) excitation 2) excitation 3) contraction 4) relaxation
48
1st step of contraction
 
arrival of nerve signal nerve signal stimulates voltage gated calcium channels that result...
49
2nd step
 
ACh is released
50
3rd step
 
ACh binds to a receptor on muscle cell
51
4th step
 
ligand gate opens and causes an end-plate potential
52
End Plate Potential
 
when Na and K channels open voltage blips from -90 to 75 quickly
53
5th step
 
opening of voltage-regulated ion gates action potentials are created
54
6th step
 
action potentials spreads down into T tubules
55
7th step
 
terminal cisternae release calcium
56
8th step
 
calcium binds to troponin
57
9th step
 
tropomyosin shifts and active sites on actin are exposed
58
10th step
 
myosin ATPase in myosin head hydrolyzes an ATP molecule, activating the head and cocking it...
59
11th step
 
myosin-actin cross bridge is formed (binds to active site on actin)
60
12th step
 
power stroke (sliding of thin filament over thick filament)
61
13th step
 
with the binding of more ATP, myosin head releases the thin filament and extends to attach...
62
14th step
 
nerve stimulation ceases and acetylcholinesterase removes ACh from receptors so stimulation...
63
15th step
 
ACh breaks down acteylcholinesterase
64
16th step
 
reabsorption of calcium ions by sarcoplasmic reticulum * calsequestrin
65
Caslsequestrin
 
isolates calcium
66
17th step
 
loss of calcium ions from troponin this moves over the active sites which stops the production...
67
18th step
 
return of tropomyosin to position blocking active sites of actin
68
Muscle TOne
 
partial contraction (makes it not flabby)
69
Length Tension Relationship
 
amount of tension generated depends on length of muscle before it was stimulated
70
Threshold
 
minimum voltage necessary to produce action potential
71
Twitch
 
a single brief stimulus at that voltage produces a quick cycle of contraction and relaxation
72
Latent Period
 
2 msec delay between the onset of stimulus and onset of twitch response
73
6 Reasons a twitch will vary in strength
 
1) stimulus frequency 2) concentration of Ca in sarcoplasm 3) how stretched a muscle was...
74
Recruitment
 
the process of bringing more motor units into play  
75
MMU
 
multiple motor unit (recruitment) ex: jug of milk, big box
76
Treppe
 
each twitch develops more tension than the one before staircase
77
Temporal Summation
 
results from 2 stimuli arriving close together
78
Wave Summation
 
results from one wave of contraction added to another
79
Incomplete Tetanus
 
each stimulus arrives before the previous twitch is over
80
Complete Tetanus
 
no time to relax between stimuli so twitches fuse into smooth prolonged contractions
81
Isometric Muscle Contraction
 
develops tension without changing length ex: the muscle tension right before you pick up something...
82
Isotonic Muscle Contraction
 
"keep same tone" concentric and eccentric
83
Concentric
 
tension development while shortening ex: curls, lifting the book
84
Eccentric
 
tension development while lengthening ex: curls, letting it back down
85
How a muscle meets immediate demand for energy
 
- short, intense exercise - 2 enzyme systems control these phosphate transfers - phosphagen...
86
Immediate demand for energy in short, intense exercise
 
Oxygen need is briefly supplied by myoglobin (stored) muscles get ATP by borrowing phosphate...
87
Myokinase
 
transfers phosphate group from one adp to another
88
Creatine Phosphate (CP)
 
phosphate-storage molecule
89
Creatine Kinase
 
obtains phosphate group from CP fast-acting system that helps maintain the ATP level while...
90
Phosphagen System
 
ATP and CP collectively provides nearly all energy used for short bursts of intense activity
91
Muscle meets Short Term demand for Energy
 
as phosphagen system is exhausted, muscles shift to anaerobic fermentation - muscles get glucose...
92
Glycogen Lactic Acid System
 
converts glucose to 2 ATP and lactic acid (toxic) in the absense of oxygen
93
Muscle meets Long Term demand for Energy
 
after a few seconds, respiratory and cardio systems catch up and deliver oxygen to the muscles...
94
Fatigue
 
progressive weakness and loss of contractility from prolonged use
95
Causes of Fatigue
 
- ATP synthesis declines as glycogen is consumed (run out of glucose) - ATP shortage - lactic...
96
Oxygen Debt
 
the difference between the resting rate of oxygen consumption and the elevated rate following...
97
EPOC
 
excess post-exercise oxygen consumption- when heavy breathing continues after strenous exercise -...
98
4 purposes of extra oxygen
 
1) replease oxygen reserves of myoglobin depleted in the first minute of exercise 2) replenish...
99
Slow Oxidative muscle fibers
 
slow-twitch, red, or type I abundant mitochondria, myoglobin and capillaries (blood) adapted...
100
Fast Glycolytic muscle fibers
 
fast-twitch, white, or type II fibers well adapted for quick responses, bur not fatigue resistance rich...
101
Factors that affect muscle strength
 
1) muscle size 2) fascicle arrangement 3) size of motor units 4) multiple motor unit summation-...
102
Resistance Exercise
 
weightlifiting stimulates cell enlargement due to synthesis of more myofilaments myofibrils...
103
Endurance Training
 
aerobic exercises produces an increase in mitochondria, glycogen, and density of capillaries
104
Skeletal vs. Smooth vs. Cardiac muscles
 
table 11.5 page 431
105
Smooth Muscles response to stretch
 
stretch opens calcium gate stress-relaxation response necessary for hollow organs that gradually...


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