Flashcard Set Preview
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| 1 |
What is your risk of developing an alcohol dependency/abuse problem if you're a male with genes...
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4-9x increase risk regardless if raised by a PWD and PWOD
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| 2 |
In women, what is alcohol preceeded by?
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Depression
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| 3 |
Do genes or environment matter more in the development of schizophrenia?
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Genes
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| 4 |
If you're raised by a PWD and have no genes for mental illness, what is your risk of developing...
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10%
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| 5 |
What variable increased risk of being a criminal?
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Genetics (although being raised by a criminal father was slightly higher than being raised...
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| 6 |
What does human cytogenics involve?
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Looking at chromosomes (karyotype maps) and related disease states)
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| 7 |
How man chromosomes does a person have?
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46
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| 8 |
What percentage of people with Down's syndrome have trisomy 21?
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Over 90%
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| 9 |
T/F Trisomy 21 is inheritable
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False. It's genetic, but occurs in mitosis (so it's not heritable)
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| 10 |
Trisomy 21 occurs in 1/? births (including or not including spontaneous abortions)
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1/650 if no including spontaneous abortion
1/200 if including spontaneous abortions
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| 11 |
What are your odds of having a child with Down's syndrome if the mother's age is over 40?
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1/30
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| 12 |
How do you diagnosis trisomy 21?
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Blood tests; ultrasound; amniocentesis
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| 13 |
What percent of amniocentesis causes abortion?
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Around 1%
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| 14 |
What do people with Down's syndrome die from?
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What looks to be like Azlheimer's (they have a lot of amyloid in their brain)
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| 15 |
What compound is involved in messenger systems, carrying amyloid/fat?
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Myo-inositol
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| 16 |
T/F Fragile X has low penetrance
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True
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| 17 |
What do people argue is the leading cause of autism?
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Fragile X
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| 18 |
What gene is involved in Fragile X?
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FMR-1 gene
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| 19 |
What is a normal amount of copies of gene involved in Fragile X? Abnormal?
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Normal: 6-54
Abnormal: 200+
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| 20 |
What is the risk of Fragile X in offpsring?
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Males: 38%
Females: 16%
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| 21 |
In which areas do people with Fragile X have more gray matter in?
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Hypothalamus
Thalamus
Caudate
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| 22 |
In which areas do people with Fragile X have less gray matter in?
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Frontal
Hippocampus
Insula
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| 23 |
In which areas is there a difference in white matter between those with Fragile X and controls?
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Temporal and frontal areas
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| 24 |
What does pleiotropy mean?
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Genetic term for the unintended consequences of genetic manipulation
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| 25 |
How are domesticated silver foxes different from wild silver foxes?
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Lower cortisol; higher serotonin; smaller jaws/teeth; floppier ears
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| 26 |
What type of interaction was involved in Ginsberg and Scott's studies?
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sex x handling x gene interaction
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| 27 |
If you're raised ina stable family, does birth trauma and violent parents matter?
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No
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| 28 |
What interaction is involved in antisocial behavior?
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MAOA and maltreatment (low MAOA and maltreatment = antisocial disorder)
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| 29 |
What makes genetics more significant?
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Number of stressful events in a person's life
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