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Mendelian Genetics Vocabulary Flashcards (:
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Side A ------ Side B Alleles ------ The different forms of a gene. Y and y are different alleles of the gene that determines seed color. Alleles occupy the same locus, or position, on chromosomes. Autosomal ------ A locus on any chromosome but a sex chromosome. Not sex-linked. Co-Dominant Alleles ------ Two different alleles at a locus are responsible for different phenotypes, and both alleles affect the phenotype of the heterozygote. Complete Linkage ------ Complete linkage describes the inheritance patterns for 2 genes on the same chromosome when the observed frequency for crossover between the loci is zero. Crossing Over ------ Exchange of genetic material between non-sister chromatids from homologous chromosome during prophase I of meiosis; results in new allele combinations Dioecious ------ Organisms produce only one type of gamete; i.e. humans Diploid ------ Cell with two of each kind of chromosome; is said to contain a diploid, or 2n, number of chromosomes Dominant Trait ------ cell with two of each kind of chromosome; is said to contain a diploid, or 2n, number of chromosomes Egg ------ haploid female sex cell produced by meiosis Epistasis ------ One gene masks the expression of a different gene for a different trait. F1 Generation ------ Offspring of a cross between true breeding plants, homozygous for the trait of interest F2 Generation ------ Offspring of a cross involving the F1 generation. Fertilization ------ fusion of male and female gametes Gamete ------ male and female sex cells, sperm and eggs Genetic Recombination ------ major source of genetic variation among organisms caused by re-assortment or crossing over during meiosis Genetics ------ branch of biology that studies heredity Genotype ------ The genetic constitution of an organism with respect to a trait. Haploid ------ cell with one of each kind of chromosome; is said to contain a haploid or n, number of chromosomes. Hemizygous ------ If there is only one copy of a gene for a particular trait In a diploid organism, the organism is hemizygous for the trait, and will display a recessive phenotype. X-linked genes in fly or human males are hemizygous. Hereditary ------ passing on of characteristics from parents to offspring Heterozygous ------ Differing alleles for a trait in an individual, such as Yy. Homologous Chromosomes ------ The pair of chromosomes in a diploid individual that have the same overall genetic content. One member of each homologous pair of chromosomes in inherited from each parent. Homozygous ------ Both alleles for a trait are the same in an individual. They can be homozygous dominant (YY), or homozygous recessive (yy). Hybrid ------ heterozygous; usually referring to the offspring of two true-breeding (homozygous) individuals differing in the traits of interest. Incomplete Dominance ------ Intermediate phenotype in F1, parental phenotypes reappear in F2. Lethal Alleles ------ Mutated genes that are capable of causing death. Linkage ------ genes that are inherited together on the same chromosome. Three inheritance patterns are possible: non-linkage, Partial linkage, and complete linkage. Meiosis ------ type of cell division where one body cell produces for gametes, each containing half the number of chromosomes in a parent’s body. Mendel's Law of Independent Assortment ------ Alleles of different genes are assorted independently of one another during the formation of gametes. Mendel's Law of Segregation ------ Alleles segregate from one another during the formation of gametes. Monoecious ------ Organisms produce both male and female gametes; i.e. garden pea. Monohybrid Cross ------ Cross involving parents differing in only one trait. Mutation ------ Change in the DNA sequence of a gene to some new, heritable form. Generally, but now always a recessive allele. Non-Disjunction ------ failure of homologous chromosomes to separate properly during meiosis; results in gametes with too many or too few chromosomes Non-Linkage ------ Non-linkage describes the inheritance patterns for 2 genes on the same chromosome, when the expected frequency for crossover between the loci is at least one. Partial Linkage ------ Partial linkage describes one of the inheritance patterns for 2 genes on the same chromosome, when the expected frequency for crossover between the loci is greater than zero but less than one. Phenotype ------ The physical appearance of an organism with respect to a trait, i.e. yellow (Y) or green (y) seeds in garden peas. Pleiotropic ------ A single gene determines more than one phenotype for an organism. Pollination ------ Transfer of male pollen grains to the pistil of a flower Polyploidy ------ The condition in which an organism has extra sets of chromosomes Probability ------ A number that describes how likely it is that an event will occur. Punnet Square ------ A chart that shows the possible combinations of alleles that result from a genetic cross. Purebred ------ The offspring of many generations that have the same traits. Recessive Trait ------ The opposite of dominant. A trait that is preferentially masked. Reciprocal Cross ------ Using male and female gametes for two different traits, alternating the source of gametes. Sex Chromosomes ------ Sex determination is based on sex chromosomes Sex-Linked ------ A gene coded on a sex chromosome, such as the X-chromosome linked genes of flies and man. Sexual Reproduction ------ pattern of reproduction that involves the production of subsequent fusion of haploid cells. Sperm ------ haploid male sex cells produced by meiosis Test Cross ------ Generally a cross involving a homozygous recessive individual. Trait ------ characteristic that is inherited; can be either dominant or recessive True-Breeding ------ Homozygous for the true-breeding trait. Wild-Type Allele ------ The non-mutant form of a gene, encoding the normal genetic function. Generally, but not always a dominant allele. Zygote ------ diploid cell formed when a sperm fertilizes an egg.
Side A ------ Side B Alleles ------ The different forms of a gene. Y and y are different alleles of the gene that determines seed color. Alleles occupy the same locus, or position, on chromosomes. Autosomal ------ A locus on any chromosome but a sex chromosome. Not sex-linked. Co-Dominant Alleles ------ Two different alleles at a locus are responsible for different phenotypes, and both alleles affect the phenotype of the heterozygote. Complete Linkage ------ Complete linkage describes the inheritance patterns for 2 genes on the same chromosome when the observed frequency for crossover between the loci is zero. Crossing Over ------ Exchange of genetic material between non-sister chromatids from homologous chromosome during prophase I of meiosis; results in new allele combinations Dioecious ------ Organisms produce only one type of gamete; i.e. humans Diploid ------ Cell with two of each kind of chromosome; is said to contain a diploid, or 2n, number of chromosomes Dominant Trait ------ cell with two of each kind of chromosome; is said to contain a diploid, or 2n, number of chromosomes Egg ------ haploid female sex cell produced by meiosis Epistasis ------ One gene masks the expression of a different gene for a different trait. F1 Generation ------ Offspring of a cross between true breeding plants, homozygous for the trait of interest F2 Generation ------ Offspring of a cross involving the F1 generation. Fertilization ------ fusion of male and female gametes Gamete ------ male and female sex cells, sperm and eggs Genetic Recombination ------ major source of genetic variation among organisms caused by re-assortment or crossing over during meiosis Genetics ------ branch of biology that studies heredity Genotype ------ The genetic constitution of an organism with respect to a trait. Haploid ------ cell with one of each kind of chromosome; is said to contain a haploid or n, number of chromosomes. Hemizygous ------ If there is only one copy of a gene for a particular trait In a diploid organism, the organism is hemizygous for the trait, and will display a recessive phenotype. X-linked genes in fly or human males are hemizygous. Hereditary ------ passing on of characteristics from parents to offspring Heterozygous ------ Differing alleles for a trait in an individual, such as Yy. Homologous Chromosomes ------ The pair of chromosomes in a diploid individual that have the same overall genetic content. One member of each homologous pair of chromosomes in inherited from each parent. Homozygous ------ Both alleles for a trait are the same in an individual. They can be homozygous dominant (YY), or homozygous recessive (yy). Hybrid ------ heterozygous; usually referring to the offspring of two true-breeding (homozygous) individuals differing in the traits of interest. Incomplete Dominance ------ Intermediate phenotype in F1, parental phenotypes reappear in F2. Lethal Alleles ------ Mutated genes that are capable of causing death. Linkage ------ genes that are inherited together on the same chromosome. Three inheritance patterns are possible: non-linkage, Partial linkage, and complete linkage. Meiosis ------ type of cell division where one body cell produces for gametes, each containing half the number of chromosomes in a parent’s body. Mendel's Law of Independent Assortment ------ Alleles of different genes are assorted independently of one another during the formation of gametes. Mendel's Law of Segregation ------ Alleles segregate from one another during the formation of gametes. Monoecious ------ Organisms produce both male and female gametes; i.e. garden pea. Monohybrid Cross ------ Cross involving parents differing in only one trait. Mutation ------ Change in the DNA sequence of a gene to some new, heritable form. Generally, but now always a recessive allele. Non-Disjunction ------ failure of homologous chromosomes to separate properly during meiosis; results in gametes with too many or too few chromosomes Non-Linkage ------ Non-linkage describes the inheritance patterns for 2 genes on the same chromosome, when the expected frequency for crossover between the loci is at least one. Partial Linkage ------ Partial linkage describes one of the inheritance patterns for 2 genes on the same chromosome, when the expected frequency for crossover between the loci is greater than zero but less than one. Phenotype ------ The physical appearance of an organism with respect to a trait, i.e. yellow (Y) or green (y) seeds in garden peas. Pleiotropic ------ A single gene determines more than one phenotype for an organism. Pollination ------ Transfer of male pollen grains to the pistil of a flower Polyploidy ------ The condition in which an organism has extra sets of chromosomes Probability ------ A number that describes how likely it is that an event will occur. Punnet Square ------ A chart that shows the possible combinations of alleles that result from a genetic cross. Purebred ------ The offspring of many generations that have the same traits. Recessive Trait ------ The opposite of dominant. A trait that is preferentially masked. Reciprocal Cross ------ Using male and female gametes for two different traits, alternating the source of gametes. Sex Chromosomes ------ Sex determination is based on sex chromosomes Sex-Linked ------ A gene coded on a sex chromosome, such as the X-chromosome linked genes of flies and man. Sexual Reproduction ------ pattern of reproduction that involves the production of subsequent fusion of haploid cells. Sperm ------ haploid male sex cells produced by meiosis Test Cross ------ Generally a cross involving a homozygous recessive individual. Trait ------ characteristic that is inherited; can be either dominant or recessive True-Breeding ------ Homozygous for the true-breeding trait. Wild-Type Allele ------ The non-mutant form of a gene, encoding the normal genetic function. Generally, but not always a dominant allele. Zygote ------ diploid cell formed when a sperm fertilizes an egg.
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