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Side A ------ Side B
developed first hybrid for an allopolyploid...used cabbage and raddish ------ Georgi Karpenchenko
what is autopolyploid...give an example ------ polyploid w/ chromosome sets from same species...ex: bananas (autotriploid: 4n x 2n --> 3n)
what is allopolyploid...give example ------ pollyplpoid w/ 2/more chromosome sets from diff species...ex: Karpenchennko making first allopolyploid w/ cabbages and raddishes
location in genome that can tolerate the introduction of transposable elements w/o negative effects on the organism ------ safe haven
give an example of a safe haven ------ arthropod R1 and R2 elements
best technique for researching gene expression ------ microarray
best technique for researching genomic regulatory sequences involving protein ------ chromatin immunoprecipitation (chIP)
technique for researching gene interaction w/in organism ------ gene knockout of the gene
used to keep gene order the same in fly stocks...used to prevent homologous crossovers so as not to keep having to screen for mutants ------ balancer chromosome
cause of most aneuploidy...abnormal segregation of homologous chromosomes or chromatids to oppostie poles at meiotic or mitotic divisions ------ nondisjunction
chromosome that lacks centromeres ------ acentric chromosome
chromosome w/ 2 centromeres ------ dicentric chromosome
crossing over between repetitiave (duplicated) DNA segments...one cause of rearrangement ------ nonallelic homologous recombination (NAHR)
rearrangement that changes gene dosage ------ unbalanced rearrangement
rearrangement that changes chromosomal gene order but doesn't remove/duplicate any DNA ------ balanced rearrangement
small deletion w/in gene...inactivates gene...has same effect as other null mutations of that gene ------ interstitial deletion
several to many genes missing...more severe ------ multigenic deletion
loop formed at meiosis by pairing of normal chromosome and deletion-containing chromosome ------ deletion loop
sudden appearance of recessive phenotype in pedigree...due to deletion of a masking dominant gene ------ pseudodominance
caused by heterozygous deletion of tip of short arm of chromosome 5 ------ cri du chat syndrome
unusual development of nervous system...caused by deletion on one homolog of chromosome 7...patient often have pronounced musical ability ------ Williams syndrome
extra copy of chromosome located adjacent to each other ------ tandem duplication
extra copy of chromosome found elsewhere ------ insertional duplication
centromere not included in inversion ------ paracentric inversion
centromere included in inversion ------ pericentric inversion
the passage of both normal chromosome to one pole and both translocated chromosomes to other pole ------ alternate segregation
plasmid or phage chromosome used to carry cloned DNA segment ------ vector

Side A ------ Side B
developed first hybrid for an allopolyploid...used cabbage and raddish ------ Georgi Karpenchenko
what is autopolyploid...give an example ------ polyploid w/ chromosome sets from same species...ex: bananas (autotriploid: 4n x 2n --> 3n)
what is allopolyploid...give example ------ pollyplpoid w/ 2/more chromosome sets from diff species...ex: Karpenchennko making first allopolyploid w/ cabbages and raddishes
location in genome that can tolerate the introduction of transposable elements w/o negative effects on the organism ------ safe haven
give an example of a safe haven ------ arthropod R1 and R2 elements
best technique for researching gene expression ------ microarray
best technique for researching genomic regulatory sequences involving protein ------ chromatin immunoprecipitation (chIP)
technique for researching gene interaction w/in organism ------ gene knockout of the gene
used to keep gene order the same in fly stocks...used to prevent homologous crossovers so as not to keep having to screen for mutants ------ balancer chromosome
cause of most aneuploidy...abnormal segregation of homologous chromosomes or chromatids to oppostie poles at meiotic or mitotic divisions ------ nondisjunction
chromosome that lacks centromeres ------ acentric chromosome
chromosome w/ 2 centromeres ------ dicentric chromosome
crossing over between repetitiave (duplicated) DNA segments...one cause of rearrangement ------ nonallelic homologous recombination (NAHR)
rearrangement that changes gene dosage ------ unbalanced rearrangement
rearrangement that changes chromosomal gene order but doesn't remove/duplicate any DNA ------ balanced rearrangement
small deletion w/in gene...inactivates gene...has same effect as other null mutations of that gene ------ interstitial deletion
several to many genes missing...more severe ------ multigenic deletion
loop formed at meiosis by pairing of normal chromosome and deletion-containing chromosome ------ deletion loop
sudden appearance of recessive phenotype in pedigree...due to deletion of a masking dominant gene ------ pseudodominance
caused by heterozygous deletion of tip of short arm of chromosome 5 ------ cri du chat syndrome
unusual development of nervous system...caused by deletion on one homolog of chromosome 7...patient often have pronounced musical ability ------ Williams syndrome
extra copy of chromosome located adjacent to each other ------ tandem duplication
extra copy of chromosome found elsewhere ------ insertional duplication
centromere not included in inversion ------ paracentric inversion
centromere included in inversion ------ pericentric inversion
the passage of both normal chromosome to one pole and both translocated chromosomes to other pole ------ alternate segregation
plasmid or phage chromosome used to carry cloned DNA segment ------ vector