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Side A ------ Side B
acetylcholine ------ neurotransmitter of the PSNS
acetylcholinersterase ------ the enzyme responsible for breaking down acetylcholine
nicotinic receptors ------ located in the ganglia of both PSNS and SNS, stimulated by alkaloid nicotine
muscarininc receptor ------ located postsynaptically in the effect organs of the PSNS, stimulated by the alkaloid muscarine
direct-binding cholinergic agonists ------ bind to cholinergic receptors, activating them
indirect-acting cholinergic agonists ------ inhibit the enzyme acetylcholinerstase, which breaks down ACh
reversible ------ bind to cholinesterase for a period of a few minutes to hours
irreversible  ------ bind to cholinesterase and form a permanent covalent bond
miosis ------ constriction of the pupil
Alzheimer's treatment ------ acetylcholine effects and stimulates muscarinic receptors - donepezil (Aricept)
donepezil (Aricept) ------ indirect-acting cholinergic drug used to treat Alzheimer's
bethanechol ------ direct-acting cholinergic used to treat urinary retention
in-direct acting drugs ------ drugs that cause skeletal muscle contraction
myasthenia gravis ------ muscle disease that breaks down the acetylcholine resulting in muscle weakness
adverse effects of cholinergics ------ result of overstimulation of the PSNS
two important adverse effects of cholinergics ------ hypotension and bradycardia
nursing implication of cholinergics ------ therapeutic effects of anti-Alzheimer's drugs may not occur for up to 6 weeks
cholinergic effect on intestine & bladder ------ increased gastric secretions, increased GI motility, increased urinary frequency
cholinergic effects on cardiovascular ------ decreased heart rate, vasodilation
receptors effected at recommended doses of cholinergics ------ muscarinic
receptors effected at high doses of cholinergics ------ nicotinic
parasympatholytics ------ drugs that block or inhibit the actions of acetylcholine in the parasympathetic nervous system
mechanism of cholinergic blockers ------ block the action of the NT acetylcholine at the muscarininc receptors in the parasympathetic nervous system
mydriasis ------ dilation of the pupil
drug of choice for bradycardia ------ atropine
cardiovascular drug effect of cholinergic blocker ------ increased heart rate
Parkinson's treatment ------ cholinergic blockers because decreased muscle rigidity and tremors - benztropine (Cogentin)
benztropine (Cogentin) ------ drug used for treatment of Parkinson's disease
atropine ------ prototype cholinergic blocker
ipratropium (Atrovent) ------ inhaler - cholinergic blocker
classic side effect of cholinergic blocker ------ decreased salivation
nursing implication for cholinergic blocker ------ dry mouth may occur --> chew gum, frequent mouth care, hard candy

Side A ------ Side B
acetylcholine ------ neurotransmitter of the PSNS
acetylcholinersterase ------ the enzyme responsible for breaking down acetylcholine
nicotinic receptors ------ located in the ganglia of both PSNS and SNS, stimulated by alkaloid nicotine
muscarininc receptor ------ located postsynaptically in the effect organs of the PSNS, stimulated by the alkaloid muscarine
direct-binding cholinergic agonists ------ bind to cholinergic receptors, activating them
indirect-acting cholinergic agonists ------ inhibit the enzyme acetylcholinerstase, which breaks down ACh
reversible ------ bind to cholinesterase for a period of a few minutes to hours
irreversible  ------ bind to cholinesterase and form a permanent covalent bond
miosis ------ constriction of the pupil
Alzheimer's treatment ------ acetylcholine effects and stimulates muscarinic receptors - donepezil (Aricept)
donepezil (Aricept) ------ indirect-acting cholinergic drug used to treat Alzheimer's
bethanechol ------ direct-acting cholinergic used to treat urinary retention
in-direct acting drugs ------ drugs that cause skeletal muscle contraction
myasthenia gravis ------ muscle disease that breaks down the acetylcholine resulting in muscle weakness
adverse effects of cholinergics ------ result of overstimulation of the PSNS
two important adverse effects of cholinergics ------ hypotension and bradycardia
nursing implication of cholinergics ------ therapeutic effects of anti-Alzheimer's drugs may not occur for up to 6 weeks
cholinergic effect on intestine & bladder ------ increased gastric secretions, increased GI motility, increased urinary frequency
cholinergic effects on cardiovascular ------ decreased heart rate, vasodilation
receptors effected at recommended doses of cholinergics ------ muscarinic
receptors effected at high doses of cholinergics ------ nicotinic
parasympatholytics ------ drugs that block or inhibit the actions of acetylcholine in the parasympathetic nervous system
mechanism of cholinergic blockers ------ block the action of the NT acetylcholine at the muscarininc receptors in the parasympathetic nervous system
mydriasis ------ dilation of the pupil
drug of choice for bradycardia ------ atropine
cardiovascular drug effect of cholinergic blocker ------ increased heart rate
Parkinson's treatment ------ cholinergic blockers because decreased muscle rigidity and tremors - benztropine (Cogentin)
benztropine (Cogentin) ------ drug used for treatment of Parkinson's disease
atropine ------ prototype cholinergic blocker
ipratropium (Atrovent) ------ inhaler - cholinergic blocker
classic side effect of cholinergic blocker ------ decreased salivation
nursing implication for cholinergic blocker ------ dry mouth may occur --> chew gum, frequent mouth care, hard candy