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Bio CHapter 12
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Side A ------ Side B What does dna stand for? ------ Deoxyribonucleic acid WHat did sutton discovery in 1903? ------ Chromosome carry inheritance WHat did morgan discover in 1911? ------ Genes are sections of chromosomes What did griffith discover in 1928? &while working with what? ------ Genetic transformation. Mouse results- injescted with live "S" ------ mouse died Mouse resuts- injected with live "r" ------ mouse lived Injected with dead "s" ------ mouse lived injected with live "r" and dead "s" ------ mouse died.*found live "s" in blood (Live "r" transformed into lives "s") WHat did avery discover in 1944? ------ showed that substance griffith discovered was DNA Chargaff, 1950? ------ analyzed base composition of DNA in cellsdiscovered amounts of adenine and thymine are almost always equalsame with guanine and cytosine Hershey and CHase 1952 ------ confirmed that generitc material is DNA not protein Franklin 1952 ------ xrayed DNA's double helix Watson &Crick 1953 ------ published double helix model of DNA Venter &Collins 2000 ------ ANNOUNCE(IN 200) published DNA sequence at human genome in DC (2003) What does a nucleotide consist of? ------ one of four possible bases (ATGC)Sugar phosphate backbone Which bases are purines? (double rings) ------ Adenine and guanine Which bases are pyramadines (single ring) ------ Thymine and Cytosine WHat are the steps of DNA SYnthasis? ------ 1) Helicase2)Primase3)polymerase(I)4)Polymerase (II)5)Ligase Helicase ------ unwinds &opens up double helixreplication fork is formed Primase ------ sets RNA as placeholder Polymerase(I) ------ adds DNA Nucleotides to open sections Polymerase (II) ------ replaces RNA primers with dna Ligase ------ fills in hoes with suar phosphate back bone Types of RNA ------ mRNArRNAtRNA mRNA ------ messengercopies DNA sequence &carries it to ribosomes rRNA ------ "ribosomal" found on ribosome tRNA ------ "transfer" carries amino acids to ribosome for assembly into proteins. types of mutations ------ Point mutationsSubstitutionInsertion and deletionchromosomal Point Mutations ------ involves on or a few nucleotidesoccurs at single point in DNA sequence Substitution ------ one base is changed to a different baseoften only affects one amino acid sometimes no effect inserition and deletion ------ AKA frame shift mutationsone or more nucleotides inserted or removed from dnathey shift the "reading frame" of the message and affect every amino acid that follows. CHromosomal Mutations ------ Involves changes in large sections of chromosomes effecting one or more gene (s)
Side A ------ Side B What does dna stand for? ------ Deoxyribonucleic acid WHat did sutton discovery in 1903? ------ Chromosome carry inheritance WHat did morgan discover in 1911? ------ Genes are sections of chromosomes What did griffith discover in 1928? &while working with what? ------ Genetic transformation. Mouse results- injescted with live "S" ------ mouse died Mouse resuts- injected with live "r" ------ mouse lived Injected with dead "s" ------ mouse lived injected with live "r" and dead "s" ------ mouse died.*found live "s" in blood (Live "r" transformed into lives "s") WHat did avery discover in 1944? ------ showed that substance griffith discovered was DNA Chargaff, 1950? ------ analyzed base composition of DNA in cellsdiscovered amounts of adenine and thymine are almost always equalsame with guanine and cytosine Hershey and CHase 1952 ------ confirmed that generitc material is DNA not protein Franklin 1952 ------ xrayed DNA's double helix Watson &Crick 1953 ------ published double helix model of DNA Venter &Collins 2000 ------ ANNOUNCE(IN 200) published DNA sequence at human genome in DC (2003) What does a nucleotide consist of? ------ one of four possible bases (ATGC)Sugar phosphate backbone Which bases are purines? (double rings) ------ Adenine and guanine Which bases are pyramadines (single ring) ------ Thymine and Cytosine WHat are the steps of DNA SYnthasis? ------ 1) Helicase2)Primase3)polymerase(I)4)Polymerase (II)5)Ligase Helicase ------ unwinds &opens up double helixreplication fork is formed Primase ------ sets RNA as placeholder Polymerase(I) ------ adds DNA Nucleotides to open sections Polymerase (II) ------ replaces RNA primers with dna Ligase ------ fills in hoes with suar phosphate back bone Types of RNA ------ mRNArRNAtRNA mRNA ------ messengercopies DNA sequence &carries it to ribosomes rRNA ------ "ribosomal" found on ribosome tRNA ------ "transfer" carries amino acids to ribosome for assembly into proteins. types of mutations ------ Point mutationsSubstitutionInsertion and deletionchromosomal Point Mutations ------ involves on or a few nucleotidesoccurs at single point in DNA sequence Substitution ------ one base is changed to a different baseoften only affects one amino acid sometimes no effect inserition and deletion ------ AKA frame shift mutationsone or more nucleotides inserted or removed from dnathey shift the "reading frame" of the message and affect every amino acid that follows. CHromosomal Mutations ------ Involves changes in large sections of chromosomes effecting one or more gene (s)
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