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Side A ------ Side B Information monitored and gathered from inside and outside the body ------ Sensory Input What is Integration? ------ processing of sensory input A response sent out to body through efferent pathway to organs like muscles or glands ------ motor output CNS defintion.... made up of what? ------ Central Nervous System..... brain and spinal cord What is the structure and function of the CNS? ------ Structure: Brain and Spinal CordFunction: Control Center and Integration of Sensory Input What are the 5 levels of awareness (from basic to vital) of the CNS ------ 1. Spinal Cord2. Brain Stem3. Brain4. Limbic System5. Cortex/Neocortex What part of the CNS handles simple jobs like basic reflexes, urination, or knee-jerk? ------ The Spinal Cord What part of the CNS handles vital signs/functions like swallowing, coughing, heart rate, or blood pressure? ------ The Brain Stem What part of the CNS contains centers for homeostasis like Thalamus, Hypothalamus, Pituitary, and Pineal glands? ------ The Brain What part of the CNS handles emotions like fear, sex drive, submission, domination, sympathy, empathy, learning, and intuition (gut feeling/warning signs)? ------ The Limbic System What part of the CNS handles consiousness, voluntary orders of movement? ------ The Cortex What part of the CNS handles higher functions like language, complex thoughts, and spacial reasoning? ------ The Neocortex What 2 regions of the CNS are connected with regard to psychosomatic diseases? ------ The Brain (homeostasis)The Limbic System (emotions) What are the effector organs in the motor output that produce a response? ------ Muscles and Glands What system is a Voluntary Motor Response? Example (1) ------ Somatic Nervous System or SNS (Skeletal Muscles) What system is an Involuntary Motor Response? Example (2) ------ Autonomic Nervous System or ANS(Visceral Muscles, Glands) What are the two subdivisions of the Autonomic Nervous System? ------ Sympathetic and Parasympathetic What is the Sympathetic Division of the ANS responsible for ? Organ Example (1) ------ Activates during activity or emergencies(Heart) What is the Parasympathetic Division of the ANS responsible for? Organ Example (1) ------ Energy Conservation, Maintenance, Housekeeping type functions(the Bladder) The Spinal and Cranial Nerves are made up of how many pairs respectively? ------ 31 and 12 What is the structure and function of the PSN ------ Structure: Cranial & Spinal NervesFunction: Communication lines between CNS & body What is the structure and function of the Sensory (afferent) Division ------ Structure: Somatic & Visceral Nerve FibersFunction: Conduct impulses to CNS What is the structure and function of the Motor (efferent) Division ------ Structure: Somatic & Autonomic Nerve FibersFunction: Conducts impulses from CNS to effectors What is the structure and function of the SNS ------ Structure: Somatic (voluntary) motorFunction: Conduct impulses from CNS to skeletal muscles What is the structure and function (2) of the ANS ------ Structure: Visceral (involuntary) motorFunction: Conduct impulses from CNS to cardiac muscles, smooth muscles and glands What is the function of the Sympathetic Division of the ANS ------ Function: Mobilizes body system during activity or emergency (heart, ex) What is the function of the Parasympathetic Division of the ANS ------ Function: Conserving Energy and Housekeeping(the bladder) What are the 2 principle Nerve Cell Types? ------ Neurons & Neuroglia (glial cells) What type of nerve cell does not expand, has limited stem cell, and is an excitable cell. ------ Neuron What type of nerve cell is a supporting cell that can grow, has stem cells, and can become cancerous ------ Neuroglia What are the 5 types of Neuroglia? ------ Astrocytes (CNS)Ependymal Cells (CNS- line brain vetricles)Microglia (CNS- brain phagocytesOligodendrocytes (CNS - myelin sheet)Schwann Cells (PNS - myelin sheet) Astrocytes (type of cell, shape, where, function (2) ------ Glial cell (Most abundant)branchedCling to neurons, capillaries & synaptic endingsControl chemical environment around synapseSupport neurons and form part of Blood, Brain, Barrier What glial cell is a brain phagocyte? ------ Microglia What glial cell lines the brain ventricles and move the cerebrospinal fluid with their cilia? ------ Ependymal Cell What glial cells form the myelin sheaths in the CNS/PNS?Which one forms neurilemma? ------ Oligodendrocytes (CNS) & Schwann Cells (PNS)Schwann Cells Neurons: Lifespan? Mitotic or Amitotic? Metabolic Rate High or Low? Function of Neuronal Membrane? ------ 100 years of moreAmitoticHighElectrical Signaling Cell Body: 2 other names? ------ Perikaryon or Soma What is the Blood-Brain Barrier ------ A separation maintained by astrocytes (a go-between) that keeps toxins flowing in the blood stream from entering the brain. What are protective, insulating coverings of neuron fibers that increase impulse speed called? ------ myelin sheaths Clusters of Neuron bodies in the CNS are called? ------ Nuclei Clusters of Neuron bodies and dendrites in the PNS are called? In the CNS? (2).... What color matter? ------ Ganglia (PNS) ** although PNS is mainly Nerves **Cortex and Basal Nuclei (CNS)Gray Armlike extensions from the cell body of all neurons ------ Processes Processes in the CNS are called? in the PNS? ------ Tracts (CNS)Nerves (PNS) What are the 2 neuron processes of the body called? ------ Dendrites and Axons Short process that is main receptive or input region. (Neurons have many of these) ------ Dendrite Single process of a Neuron that is typically very long and conducts impulses away from cell body ------ Axon Occasional 'fork in the road' of an axon ------ Axon Collateral End of the road of an axon (branched profusely) (3 different names) ------ Axon TerminalSynaptic KnobBouton ('button') The initial, cone-shaped region of a neuron's conducting process ------ Axon Hillock A LONG axon is called? ------ Nerve Fiber Signals sent TOWARD the cell body from the dendrites needs to be added up....called? ------ Graded Potential impulses are generated in the region between the axon hillock and the axon and called? ------ Trigger Zone impulses are conveyed along the axon to the axon terminals which are the ___________ region of the neuron? ------ Secretory Region Signaling chemicals stored in vesicles at the axon terminals? ------ Neurotransmitters The nucleus and cytoplasmic bulge on the myelin sheath of Schwann Cells is called? ------ Neurilemma Schwann cells leave gaps between each other at regular intervals called? ------ Nodes of Ranvier The brain's white matter is composed of ? The gray matter? ------ Myelinated Fibers (White)Nerve Cell Bodies and Unmyelinated Fibers (Gray) What is the plasma membrane region of the axon through which the impulse is conducted? ------ Axolemma Where can pharmaceuticals effect, enhance, or stop signals? ------ Synapse/ Axon Terminal / Bouton Transport proteins direction that move material toward axon terminal? What would move in this direction? ------ Anterogrademitochondria, membrane components, enzymes Transport proteins direction that move material toward cell body? What would move in this direction? ------ Retrogradeorganelles for degrading, signaling molecules, viruses (Rabies & Herpes), and bacterial toxins (bad) Neurotransmitters function is to __________ or _________ other cell bodies ------ Stimulate or Inhibit 'AP' stand for? and it travels over what? ------ Action PotentialAxolemma Clusters of myelinated fibers in the CNS called? (2) ....in the PNS? What color matter? ------ Tracts or Columns (CNS)Nerves (PNS)White What are the 3 types of Neurons? ------ Sensory (Afferent)Interneuron (Shuttle between)Motor (Efferent) Which is faster Continuous Conduction (unmyelated) or Saltatory Conduction (myelated)? How much faster? Why? ------ Saltatory Conduction30 times fasterInsulation prevents ion/voltage leakage so impulse doesn't decay Neurons that make up 99% of the neurons in the body? ------ Interneurons What membrane channels are always open? (2 names) ------ Leakage Channels or Non-Gated Channels What membrane channels open when a neurotransmitter binds? (2 names) ------ Chemically Gated or Ligand-Gated Channels What membrane channels open/close in response to changes in membrane potential? ------ Voltage-gated Channels Movement according to concentration gradient and electrical gradient (opposite charges) forms what type of cumulative gradient? ------ Electrochemical Gradient What is the approximate mV of a membrane (inside or cytoplasmic side) at Resting Membrane Potential?Why negative? ------ -70mVK+ diffuses out of cell (toward it's low gradient) faster than Na+ can diffuse in (toward it's low gradient) which ion, K+ or Na+, is in greater quantity inside the cell?outside cell? ------ K+ (inside)Na+ (outside) What stops Na+ and K+ diffusion through membrane from becoming even? ------ Sodium-Potassium Pump pumps out 3 Na+ and brings in 2 K+, maintaining/restoring -70mV When the mV of a membrane becomes less negative (moves closer to zero or above zero) it is called? ------ Depolarization When the mV of a membrane becomes more negative (moves further from zero or resting potential) it is called? ------ Hyperpolarization Changes in the membrane potential can produce what 2 types of signals? ------ Graded Potentials (short, incoming signals-Dendrites)Action Potentials (long, outgoing signals-Axons) Cell membranes that conduct impulses over muscles fibers are called? ------ Sarcolemma What are the two synaptic gap junctions that signals are sent over called? ------ Neuroneural Junctions (NNJ)Neuromuscular Junctions (NMJ) In order for a neuron to signal, the AP must be __________ along the axon's entire length ------ Propogated (then it is self-propogated once threshold is reached) What is sodium's voltage-gated channel's 'Threshold of Sensitivity' ? ------ -55mV Once local voltage causes a threshold to be reached and a self-propogating depolarization occurs, what is generated? ------ an Action Potential outgoing signals are ____________potential and go over the __________membrane.incoming signals are ___________potential and go over the __________membrane ------ Action (potential) / AxolemmaGraded (potential) / Dendrolemma What is the total amplitude of an Action Potential (AP) ------ 100mV (-70mV to +30mV) Do Graded Potentials decrease over distance/time? Action Potentials? ------ Graded - yesAction - no Repolarization (AP-3) restores which, resting electrical conditions or resting ionic conditions? ------ Resting Electrical Conditions What restores resting ionic conditions after AP? ------ Sodium-Potassium Pump The CNS determines the intensity of a stimulus by what? ------ Frequency of impulses Action Potential is a brief ______________________ ------ reversal of the membrane potential (charge) AP's resting state has ________ion channels open and ___________ ion channels closed. ------ Leakage (open)Na+ and K+ (closed) AP conduction is called a ____________. ------ Propogation No impulses can go through during the ________period, and only extremely strong impulses can go through during the ________period. ------ Absolute Refractory PeriodRelative Refractory Period Conducts an impulse toward a synapse ------ Presynaptic Neuron Conducts an impulse away from a synapse ------ Postsynaptic Neuron What are the 3 types of Synapses? ------ Axodendritic SynapseAxosomatic SynapseAxoaxonic Synapse A Chemical Synapse is typically composes of what two parts? ------ Axon Terminal containing synaptic vessicles (w/ neurotransmitters) of presynaptic NeuronReception region of postsynaptic neuron Neurotransmitter release from presynaptic neuron across synaptic cleft to receptor region of postsynaptic cleft ensures that what will happen? ------ Unidirectional communication between neurons. What kind of channels are on the postsynaptic neuron at the synaptic cleft? ------ Ligand-gated channels (or chemical-gated channels) What 3 possible events happen to the neurotransmitter once the effect is terminated? ------ Reuptake (in presynaptic neuron)Degradation (by enzymes in extracellular fluid)Diffusion away (from Synaptic Cleft in ECF) When neurotransmitter binds to the ligand-gated channel, what happens? (2) ------ Ion gradient flow (Na+/K+)Graded Potential (along postsynaptic membrane/cycle repeats) How long is Synaptic Delay? ------ 0.3 - 5.0 ms a depolarization of the postsynaptic membrane that results in the opening of Na+/K+ channels and a graded potential, bringing the membrane closer to an AP threshold. ------ Excitatory Postsynaptic Potential (EPSP) a hyperpolarization of the postsynaptic membrane that results in the opening of K+/Cl- and movement AWAY from the AP threshold ------ Inhibitory Postsynaptic Potential (IPSP) What is responsible for the coupling of excitation and contraction of skeletal muscle fibers? ------ Calcium A 'Triad' is made up of what? ------ 2 terminal cisternae and 1 Terminal (T) Tubule The Terminal Cisternae of the Sarcoplasmic Reticulum (SR) is connected to the T Tubule via what? ------ Voltage-gated Calcium Channels (proteins) When calcium ions bind to troponin, what happens? ------ Troponin changes shape and causes the bound tropomyosin to move off of Actin binding sites. What type of tranport causes Ca+, Na+, and K+ to return to their resting ionic potential? ------ Active Transport via ATP driven pumps granules of stored glycogen that provide glucose during periods of muscle cell activity ------ glycosomes Red pigment in muscles that store oxygen ------ myoglobin Giant protein elastic filament that attaches to the Z disc and the thick filament that helps the muscle cell spring back after being stretched ------ Titin The name of the neurotransmitter released into synaptic cleft of Neuromuscular Junction for contractions, also CNS, and some ANS neurons? ------ Acetylcholine (ACh) Enzymatic breakdown of ACh is done by what enzyme?What is ACh broken down into? ------ AcetylcholinesteraseAcetic Acid & Choline One or more presynaptic neurons transmit impulses in rapid-fire order during __________ summation ------ Temporal Postsynaptic neuron is stimulated by a large number of terminals at the same time during ___________ summation. ------ Spatial Dopamine, NADR (NE)/ADR, Serotonin, and Histamine are types of what and part of this group ------ NeurotransmittersBiological Amines GABA and Glutamate are types of what and part of this group.Which is excitatory and which is inhibitory? ------ NeurotransmittersAmino AcidsGABA - InhibitoryGlutamate - Excitatory Substance P and Endorphins are types of what and part of this group.Which is excitatory and which is inhibitory? ------ NeurotransmittersPeptidesSubstance P - ExcitatoryEndorphins - Inhibitory Morphine, Heroin, and Methadone mimic what? ------ Endorphins Coffee, Tea, and Chocolate work by doing what? ------ Blocking receptor sites for inhibitory neurotransmitter in sleep-wake cycle, Adenosine. Inhibitory neurotransmitter in sleep-wake cycle ------ Adenosine Neurotransmitter, Endocannabinoid, is linked to what drug and it's effects? ------ Marijuana, increased appetite, memory loss What type processing when one input travels one pathway to a specific destination resulting in the same, predictable response? Example? ------ Serial ProcessingReflexes What type of processing when one input travels along several pathways producing several responses. Example? ------ Parallel ProcessingA smell reminds of the odor and an associated experience. Acetylcholine (ACh) is an excitatory neurotransmitter except in the _______________ ------ Heart Inhibitory CNS amino acid neurotransmitter is ___________, and excitatory is ____________ ------ GABAGlutamate Substance P is blocked by ___________ ------ Endorphins
Side A ------ Side B Information monitored and gathered from inside and outside the body ------ Sensory Input What is Integration? ------ processing of sensory input A response sent out to body through efferent pathway to organs like muscles or glands ------ motor output CNS defintion.... made up of what? ------ Central Nervous System..... brain and spinal cord What is the structure and function of the CNS? ------ Structure: Brain and Spinal CordFunction: Control Center and Integration of Sensory Input What are the 5 levels of awareness (from basic to vital) of the CNS ------ 1. Spinal Cord2. Brain Stem3. Brain4. Limbic System5. Cortex/Neocortex What part of the CNS handles simple jobs like basic reflexes, urination, or knee-jerk? ------ The Spinal Cord What part of the CNS handles vital signs/functions like swallowing, coughing, heart rate, or blood pressure? ------ The Brain Stem What part of the CNS contains centers for homeostasis like Thalamus, Hypothalamus, Pituitary, and Pineal glands? ------ The Brain What part of the CNS handles emotions like fear, sex drive, submission, domination, sympathy, empathy, learning, and intuition (gut feeling/warning signs)? ------ The Limbic System What part of the CNS handles consiousness, voluntary orders of movement? ------ The Cortex What part of the CNS handles higher functions like language, complex thoughts, and spacial reasoning? ------ The Neocortex What 2 regions of the CNS are connected with regard to psychosomatic diseases? ------ The Brain (homeostasis)The Limbic System (emotions) What are the effector organs in the motor output that produce a response? ------ Muscles and Glands What system is a Voluntary Motor Response? Example (1) ------ Somatic Nervous System or SNS (Skeletal Muscles) What system is an Involuntary Motor Response? Example (2) ------ Autonomic Nervous System or ANS(Visceral Muscles, Glands) What are the two subdivisions of the Autonomic Nervous System? ------ Sympathetic and Parasympathetic What is the Sympathetic Division of the ANS responsible for ? Organ Example (1) ------ Activates during activity or emergencies(Heart) What is the Parasympathetic Division of the ANS responsible for? Organ Example (1) ------ Energy Conservation, Maintenance, Housekeeping type functions(the Bladder) The Spinal and Cranial Nerves are made up of how many pairs respectively? ------ 31 and 12 What is the structure and function of the PSN ------ Structure: Cranial & Spinal NervesFunction: Communication lines between CNS & body What is the structure and function of the Sensory (afferent) Division ------ Structure: Somatic & Visceral Nerve FibersFunction: Conduct impulses to CNS What is the structure and function of the Motor (efferent) Division ------ Structure: Somatic & Autonomic Nerve FibersFunction: Conducts impulses from CNS to effectors What is the structure and function of the SNS ------ Structure: Somatic (voluntary) motorFunction: Conduct impulses from CNS to skeletal muscles What is the structure and function (2) of the ANS ------ Structure: Visceral (involuntary) motorFunction: Conduct impulses from CNS to cardiac muscles, smooth muscles and glands What is the function of the Sympathetic Division of the ANS ------ Function: Mobilizes body system during activity or emergency (heart, ex) What is the function of the Parasympathetic Division of the ANS ------ Function: Conserving Energy and Housekeeping(the bladder) What are the 2 principle Nerve Cell Types? ------ Neurons & Neuroglia (glial cells) What type of nerve cell does not expand, has limited stem cell, and is an excitable cell. ------ Neuron What type of nerve cell is a supporting cell that can grow, has stem cells, and can become cancerous ------ Neuroglia What are the 5 types of Neuroglia? ------ Astrocytes (CNS)Ependymal Cells (CNS- line brain vetricles)Microglia (CNS- brain phagocytesOligodendrocytes (CNS - myelin sheet)Schwann Cells (PNS - myelin sheet) Astrocytes (type of cell, shape, where, function (2) ------ Glial cell (Most abundant)branchedCling to neurons, capillaries & synaptic endingsControl chemical environment around synapseSupport neurons and form part of Blood, Brain, Barrier What glial cell is a brain phagocyte? ------ Microglia What glial cell lines the brain ventricles and move the cerebrospinal fluid with their cilia? ------ Ependymal Cell What glial cells form the myelin sheaths in the CNS/PNS?Which one forms neurilemma? ------ Oligodendrocytes (CNS) & Schwann Cells (PNS)Schwann Cells Neurons: Lifespan? Mitotic or Amitotic? Metabolic Rate High or Low? Function of Neuronal Membrane? ------ 100 years of moreAmitoticHighElectrical Signaling Cell Body: 2 other names? ------ Perikaryon or Soma What is the Blood-Brain Barrier ------ A separation maintained by astrocytes (a go-between) that keeps toxins flowing in the blood stream from entering the brain. What are protective, insulating coverings of neuron fibers that increase impulse speed called? ------ myelin sheaths Clusters of Neuron bodies in the CNS are called? ------ Nuclei Clusters of Neuron bodies and dendrites in the PNS are called? In the CNS? (2).... What color matter? ------ Ganglia (PNS) ** although PNS is mainly Nerves **Cortex and Basal Nuclei (CNS)Gray Armlike extensions from the cell body of all neurons ------ Processes Processes in the CNS are called? in the PNS? ------ Tracts (CNS)Nerves (PNS) What are the 2 neuron processes of the body called? ------ Dendrites and Axons Short process that is main receptive or input region. (Neurons have many of these) ------ Dendrite Single process of a Neuron that is typically very long and conducts impulses away from cell body ------ Axon Occasional 'fork in the road' of an axon ------ Axon Collateral End of the road of an axon (branched profusely) (3 different names) ------ Axon TerminalSynaptic KnobBouton ('button') The initial, cone-shaped region of a neuron's conducting process ------ Axon Hillock A LONG axon is called? ------ Nerve Fiber Signals sent TOWARD the cell body from the dendrites needs to be added up....called? ------ Graded Potential impulses are generated in the region between the axon hillock and the axon and called? ------ Trigger Zone impulses are conveyed along the axon to the axon terminals which are the ___________ region of the neuron? ------ Secretory Region Signaling chemicals stored in vesicles at the axon terminals? ------ Neurotransmitters The nucleus and cytoplasmic bulge on the myelin sheath of Schwann Cells is called? ------ Neurilemma Schwann cells leave gaps between each other at regular intervals called? ------ Nodes of Ranvier The brain's white matter is composed of ? The gray matter? ------ Myelinated Fibers (White)Nerve Cell Bodies and Unmyelinated Fibers (Gray) What is the plasma membrane region of the axon through which the impulse is conducted? ------ Axolemma Where can pharmaceuticals effect, enhance, or stop signals? ------ Synapse/ Axon Terminal / Bouton Transport proteins direction that move material toward axon terminal? What would move in this direction? ------ Anterogrademitochondria, membrane components, enzymes Transport proteins direction that move material toward cell body? What would move in this direction? ------ Retrogradeorganelles for degrading, signaling molecules, viruses (Rabies & Herpes), and bacterial toxins (bad) Neurotransmitters function is to __________ or _________ other cell bodies ------ Stimulate or Inhibit 'AP' stand for? and it travels over what? ------ Action PotentialAxolemma Clusters of myelinated fibers in the CNS called? (2) ....in the PNS? What color matter? ------ Tracts or Columns (CNS)Nerves (PNS)White What are the 3 types of Neurons? ------ Sensory (Afferent)Interneuron (Shuttle between)Motor (Efferent) Which is faster Continuous Conduction (unmyelated) or Saltatory Conduction (myelated)? How much faster? Why? ------ Saltatory Conduction30 times fasterInsulation prevents ion/voltage leakage so impulse doesn't decay Neurons that make up 99% of the neurons in the body? ------ Interneurons What membrane channels are always open? (2 names) ------ Leakage Channels or Non-Gated Channels What membrane channels open when a neurotransmitter binds? (2 names) ------ Chemically Gated or Ligand-Gated Channels What membrane channels open/close in response to changes in membrane potential? ------ Voltage-gated Channels Movement according to concentration gradient and electrical gradient (opposite charges) forms what type of cumulative gradient? ------ Electrochemical Gradient What is the approximate mV of a membrane (inside or cytoplasmic side) at Resting Membrane Potential?Why negative? ------ -70mVK+ diffuses out of cell (toward it's low gradient) faster than Na+ can diffuse in (toward it's low gradient) which ion, K+ or Na+, is in greater quantity inside the cell?outside cell? ------ K+ (inside)Na+ (outside) What stops Na+ and K+ diffusion through membrane from becoming even? ------ Sodium-Potassium Pump pumps out 3 Na+ and brings in 2 K+, maintaining/restoring -70mV When the mV of a membrane becomes less negative (moves closer to zero or above zero) it is called? ------ Depolarization When the mV of a membrane becomes more negative (moves further from zero or resting potential) it is called? ------ Hyperpolarization Changes in the membrane potential can produce what 2 types of signals? ------ Graded Potentials (short, incoming signals-Dendrites)Action Potentials (long, outgoing signals-Axons) Cell membranes that conduct impulses over muscles fibers are called? ------ Sarcolemma What are the two synaptic gap junctions that signals are sent over called? ------ Neuroneural Junctions (NNJ)Neuromuscular Junctions (NMJ) In order for a neuron to signal, the AP must be __________ along the axon's entire length ------ Propogated (then it is self-propogated once threshold is reached) What is sodium's voltage-gated channel's 'Threshold of Sensitivity' ? ------ -55mV Once local voltage causes a threshold to be reached and a self-propogating depolarization occurs, what is generated? ------ an Action Potential outgoing signals are ____________potential and go over the __________membrane.incoming signals are ___________potential and go over the __________membrane ------ Action (potential) / AxolemmaGraded (potential) / Dendrolemma What is the total amplitude of an Action Potential (AP) ------ 100mV (-70mV to +30mV) Do Graded Potentials decrease over distance/time? Action Potentials? ------ Graded - yesAction - no Repolarization (AP-3) restores which, resting electrical conditions or resting ionic conditions? ------ Resting Electrical Conditions What restores resting ionic conditions after AP? ------ Sodium-Potassium Pump The CNS determines the intensity of a stimulus by what? ------ Frequency of impulses Action Potential is a brief ______________________ ------ reversal of the membrane potential (charge) AP's resting state has ________ion channels open and ___________ ion channels closed. ------ Leakage (open)Na+ and K+ (closed) AP conduction is called a ____________. ------ Propogation No impulses can go through during the ________period, and only extremely strong impulses can go through during the ________period. ------ Absolute Refractory PeriodRelative Refractory Period Conducts an impulse toward a synapse ------ Presynaptic Neuron Conducts an impulse away from a synapse ------ Postsynaptic Neuron What are the 3 types of Synapses? ------ Axodendritic SynapseAxosomatic SynapseAxoaxonic Synapse A Chemical Synapse is typically composes of what two parts? ------ Axon Terminal containing synaptic vessicles (w/ neurotransmitters) of presynaptic NeuronReception region of postsynaptic neuron Neurotransmitter release from presynaptic neuron across synaptic cleft to receptor region of postsynaptic cleft ensures that what will happen? ------ Unidirectional communication between neurons. What kind of channels are on the postsynaptic neuron at the synaptic cleft? ------ Ligand-gated channels (or chemical-gated channels) What 3 possible events happen to the neurotransmitter once the effect is terminated? ------ Reuptake (in presynaptic neuron)Degradation (by enzymes in extracellular fluid)Diffusion away (from Synaptic Cleft in ECF) When neurotransmitter binds to the ligand-gated channel, what happens? (2) ------ Ion gradient flow (Na+/K+)Graded Potential (along postsynaptic membrane/cycle repeats) How long is Synaptic Delay? ------ 0.3 - 5.0 ms a depolarization of the postsynaptic membrane that results in the opening of Na+/K+ channels and a graded potential, bringing the membrane closer to an AP threshold. ------ Excitatory Postsynaptic Potential (EPSP) a hyperpolarization of the postsynaptic membrane that results in the opening of K+/Cl- and movement AWAY from the AP threshold ------ Inhibitory Postsynaptic Potential (IPSP) What is responsible for the coupling of excitation and contraction of skeletal muscle fibers? ------ Calcium A 'Triad' is made up of what? ------ 2 terminal cisternae and 1 Terminal (T) Tubule The Terminal Cisternae of the Sarcoplasmic Reticulum (SR) is connected to the T Tubule via what? ------ Voltage-gated Calcium Channels (proteins) When calcium ions bind to troponin, what happens? ------ Troponin changes shape and causes the bound tropomyosin to move off of Actin binding sites. What type of tranport causes Ca+, Na+, and K+ to return to their resting ionic potential? ------ Active Transport via ATP driven pumps granules of stored glycogen that provide glucose during periods of muscle cell activity ------ glycosomes Red pigment in muscles that store oxygen ------ myoglobin Giant protein elastic filament that attaches to the Z disc and the thick filament that helps the muscle cell spring back after being stretched ------ Titin The name of the neurotransmitter released into synaptic cleft of Neuromuscular Junction for contractions, also CNS, and some ANS neurons? ------ Acetylcholine (ACh) Enzymatic breakdown of ACh is done by what enzyme?What is ACh broken down into? ------ AcetylcholinesteraseAcetic Acid & Choline One or more presynaptic neurons transmit impulses in rapid-fire order during __________ summation ------ Temporal Postsynaptic neuron is stimulated by a large number of terminals at the same time during ___________ summation. ------ Spatial Dopamine, NADR (NE)/ADR, Serotonin, and Histamine are types of what and part of this group ------ NeurotransmittersBiological Amines GABA and Glutamate are types of what and part of this group.Which is excitatory and which is inhibitory? ------ NeurotransmittersAmino AcidsGABA - InhibitoryGlutamate - Excitatory Substance P and Endorphins are types of what and part of this group.Which is excitatory and which is inhibitory? ------ NeurotransmittersPeptidesSubstance P - ExcitatoryEndorphins - Inhibitory Morphine, Heroin, and Methadone mimic what? ------ Endorphins Coffee, Tea, and Chocolate work by doing what? ------ Blocking receptor sites for inhibitory neurotransmitter in sleep-wake cycle, Adenosine. Inhibitory neurotransmitter in sleep-wake cycle ------ Adenosine Neurotransmitter, Endocannabinoid, is linked to what drug and it's effects? ------ Marijuana, increased appetite, memory loss What type processing when one input travels one pathway to a specific destination resulting in the same, predictable response? Example? ------ Serial ProcessingReflexes What type of processing when one input travels along several pathways producing several responses. Example? ------ Parallel ProcessingA smell reminds of the odor and an associated experience. Acetylcholine (ACh) is an excitatory neurotransmitter except in the _______________ ------ Heart Inhibitory CNS amino acid neurotransmitter is ___________, and excitatory is ____________ ------ GABAGlutamate Substance P is blocked by ___________ ------ Endorphins
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