Rapid, Short, Intermediate, And Long Acting Insulins

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Rapid Acting Insulins Lispro= humalog
Aspart= novolog
Rapid Acting Insulin
Onset of action
peak action
duration of action
onset= 5-15 minutes for both
peak= lispro: 1 hr; aspart: 40-50 minutes
duration= lispro: 3hr; aspart: 4-6 hr
Time for adverse reaction
Rapid Acting Insulin

Midmorning; trembling and weakness
Characteristics of
Rapid Acting Insulin
pt should eat within 5-15 minutes after injection; its also used in insulin pumps
Short acting Insulin Regular Insulin (Humalin R, Novolin R, Iletin II Regular)
Short Acting Insulin
Onset of action
peak action
duration of action
onset= 30-60 mins
peak= 2-3 hr
duration= 4-6 hr
Time of Adverse Reaction
Short Acting Insulin
Midmorning
Midafternoon= weakness and fatigue
Characteristics of short Acting insulin its a clear solution given 20-30 minutes before meals, can be given alone or with other insulins.
Intermediate Acting Insulin NPH (isophane)
Intermediate Acting Insulin
Onset of action
peak action
duration of action
onset= 2-4 hr
peak= 6-12 hr
duration= 16-20 hr
Time for adverse Reactions
intermediate Acting Insulin
Early evening= wekaness and fatigue
Characteristics of Intermediate Acting Insulin white and clloudy solution, and can be given after meals
Long acting Insulin Glargine(Lantus)
Long Acting Insulin
Onset of action
peak action
duration of action
Onset= 1 hr
Peak= Continous no Peak
duration= 24 hr
Characterisitcs for long acting insulin maintains blood glcose levels regardless of meals, CANNOT BE MIXED WITH OTHER INSULIN. This is given at bedtime, hours of sleep (hs)
the action of all insulins to reduce blood glucose levels by increasing glucose tranport to cell membranes; it also enhances the conversion of glucose to glycogen.
Education for pts taking Insulins rotate sites for injections to prevent lipohypertrophy, or fibropatty masses at injection sites. Only regular insulin can be given IV, THE REST CAN ALL BE GIVEN SQ
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