Nursing Drug Cards

Total Flash Cards » 4
 
1. 

Brand Name: Lyrica

Generic Name: Pregabalin

Classification: Anticonvulsant, gaba-analog, analgesic, anxiolytic

Therapeutic: anticonvulsant, analgesic, anti-anxiety

Dosages and route: Neuropathic Pain, adult 50-100 mg tid

 

Action and therapeutic effect: pregabalin is an analog of gamma-aminobutyric acid (GABA). It is structurally related to gabapentin, but shows greater potency in pain and seizure disorders (3-10 times greater). The exact mechanism of action of pregabalin as an anti-seizure agent is unknown. it increases neuronal GABA levels and reduces calcium currents in the calcium channels of neurons. this may account for its control of pain and anxiety. (unlabeled use: treatment of moderate use)

Side Effects: dizziness, weight gain, headache, speech disorder, constipation, dry mouth, increase appetite, vomiting, abnormal vision, blurry vision.

Nursing Implication: Monitor for weight gain, signs and symptoms’ of heart failure. Supervise ambulation. Report changes in vision, dizziness, and weakness to physician. Avoid alcohol while taking drug.

 
2. 

Brand Name: Celexa

Generic Name: Citalopram Hydrobromide

Classification: Psychotherapeutic agent, selective serotonin-reuptake inhibitor.

Therapeutic: Anti-depressant

Dosages and route: Depression: Adult & Geriatric: PO 20 mg QD

 

Action and therapeutic effect: Selective serotonin reuptake inhibitor in the CNS. Antidepressant effect is presumed to be linked to its inhibition of CNS presynaptic neuronal uptake of serotonin which results in antidepressant activity. Uses: Depression

Side Effects: Fatigue, fever, tachycardia, nausea, vomiting, abdominal pain, dry mouth, dizziness, insomnia, anxiety, migraine, increased sweating.

Nursing Implications: Watch closely for worsening of depression or emergence of suicidal ideations. Monitor periodically HR and BP and carefully monitor complete cardiac status in person with suspected cardiac disease. Avoid using alcohol while taking this drug.

 
3. 

Brand Name: Prinivil, Zestril

Generic Name: Lisinopril

Classification: Angiotensin-converting enzyme (ACE) inhibitor; antihypertensive agent.

Therapeutic: Antihypertensive agent; ACE inhibitor

Dosages and route: Hypertension PO 10 mg qd; Heart failure PO 5-40 mg QD

 

Action and therapeutic effect: Lowers BP by specific inhibition of the angiotensin-converting enzyme (ACE). This interrupts conversion sequences initiated by renin that form angiotensin II, a potent vasoconstrictor. ACE inhibition alters hemodynamics without compensatory reflex tachycardia or changes in cardiac output. Improved cardiac outputand exercise tolerance due to inhibition of ACE also decreases circulating aldosterone, which is normally released in response to angiotensin II stimulation. Reduced aldosterone is associated with a potassium-sparing effect. also decrease peripheral resistance and pulmonary vascular resistance.

Side Effects: Headache, dizziness, fatigue, chest pain, hypotension, nausea, vomiting, diarrhea, constipation, cough.

Nursing Implications: Place patient in supine position and notify physician if sudden severe hypotension occurs within the first 1-5 hours after initial does. Measure BP prior to dosing to determine whether satisfactory control is being maintained for 24 hours. Be aware of importance of proper diet, including sodium and potassium restrictions. Do not use substitute containing potassium.

 
4. 

Brand Name: Zocor

Generic Name: Simvastatin

Classification: HMG-COA Reductase inhibitor (statin), antilipemic

Therapeutic: antihyperlipemic; statin

Dosages and route: hyperchloesterolemia adult PO 5-40 mg qd

 

Action and therapeutic effect: Inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase; similar in action to lovastatin but more potent, HMG-CoA reductase inhibitors increase HDL cholesterol, and decrease LDL cholesterol, and total cholesterol synthesis. Effectiveness indicated by decreased serum triglycerides, decreased LDL, cholesterol, and modest increases in HDL cholesterol.

Side Effects: dizziness, headache, fatigue, insomnia, nausea, diarrhea, vomiting, abdominal pain, heartburn, cough.

Nursing Implications: Asses for report unexplained muscle pain. Determine CPK level at onset of muscle pain. Report unexplained muscle pain, tenderness, or weakness to physician. Moderate intake of grapefruit juice while taking this medication.